Description
Technical: Flubendiamide 39.35% SC.
Fame contains Flubendiamide which is the first representative of a new chemical insecticide classes – the diamides. In contrast to other insecticide classes targeting the insect nervous system, Flubendiamide acts at receptors in insect muscles causing an immediate cessation of feeding and thus avoids crop damage. It is well suited for the control of a broad range of Lepidoptera pests. The unique mode of action makes the compound well suited as a tool in insect resistance management programmes.
MODE OF ACTION
In contrast to most commercially successful insecticides which act on the nervous system, Flubendiamide disrupts proper muscle function in insects and therefore represents a novel, unique mode of action. These characteristic symptoms are induced by Flubendiamide through the activation of ryanodinesensitive intracellular calcium release channels (ryanodine receptors, RyR) as shown by Ca2+ fluorescence measurements in insect neurons as well as in recombinant cells expressing the cloned ryanodine receptor from Drosophila melanogaster.
Insecticide Resistance Action Committee (IRAC) Classification No. 28
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